Bioactive Metal Oxide Nanocomposites: Synthesis, Characterization, and Applications of Core-Shell Structures for Enhanced Bone Strength

Description

This book presents an in-depth exploration into the synthesis, characterization, and biomedical application of bioactive metal oxide nanocomposites, with a special focus on ZnO/MgO core-shell structures for enhancing bone strength. Rooted in rigorous academic research, it blends fundamental nanotechnology with practical biomedical engineering to address current challenges in orthopedic material science. The book systematically covers the synthesis of ZnO and MgO nanoparticles using both sol-gel and hydrothermal methods, optimized for purity, morphology, and functionality. A key feature of the work is the formulation of core-shell nanostructures that harness the unique properties of both ZnO and MgO, with ZnO contributing to antimicrobial and osteogenic behavior, and MgO promoting osteoblast proliferation and mechanical reinforcement. These core-shell nanoparticles were integrated into hydroxyapatite (HA)-based composites in varying doping concentrations to study their effect on biocompatibility and mechanical properties. Detailed characterization using X-ray Diffraction (XRD) and Scanning Electron Microscopy (SEM) provides insights into the structural and morphological evolution of the synthesized materials. Biological assessments, including antimicrobial activity and RBC lysis tests, alongside compression testing, highlight the dual bio-functional and load-bearing capabilities of the designed nanocomposites. This book will serve as a valuable resource for researchers, engineers, and graduate students working in the fields of nanomaterials, biomaterials, and biomedical device design. It not only introduces novel synthetic strategies and characterization approaches but also contributes significantly to the growing body of knowledge in bone tissue engineering and implantable material science. Whether you’re delving into nanotechnology for orthopedic applications or seeking scalable, biofunctional composite solutions, this book offers a comprehensive and practical guide grounded in original, application-oriented research.